Father Factor V Leiden
Most people with factor v leiden never develop abnormal clots.
Father factor v leiden. This mutation can increase your chance of developing abnormal blood clots most commonly in your legs or lungs. This gene plays a role in how your body forms blood clots after an injury. Factor v leiden is the most common of the inherited clotting disorder and occurs in all races and ethnicities. It can cause a disorder called factor v leiden thrombophilia.
When you get a cut or. Factor v leiden fvl is a change in your genes that keeps your body s blood clotting process from working right. Factor v leiden is the name of a specific gene mutation in the f5 gene. If you have factor v leiden you have a greater chance of developing blood clots.
It is named after the dutch city leiden where it was first identified in 1994 by prof r. Bertina under the direction of and in the laboratory of prof p. This makes blood clots more likely to form a condition called thrombophilia. The factor v leiden protein is harder to turn off than the normal factor v protein.
What is factor v leiden. The amount of abnormal factor v and the severity of disease depends on the presence of one or two copies of the mutated gene. The incidence in this population is estimated to be 3 7. An abnormality in the affected individual s dna results in the production of an abnormal form of factor v.
People can inherit one or two copies of the factor v leiden gene mutation. Had the flu could have been swine flu or even covid judging by the symptoms both are also known to cause dvts in younger people and decided to take ibuprofen known to increase dvt and leg swelling this eventually led to me having a dvt in my right leg. Factor v leiden is a genetic disorder. Factor v leiden fak tur five lide n is a mutation of one of the clotting factors in the blood.
It is most common in caucasians from central and northern europe. But in people who do these abnormal clots can lead to long term health problems or become life threatening. Factor v leiden is the most common genetic predisposition to blood clots. Factor v leiden is the most common hereditary hypercoagulability prone to clotting disorder amongst ethnic europeans.